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Hydrocortisone acetate

JP15,USP,EP5.0,BP2007

 

 

ITEMS

STANDARD

RESULTS

Appearance

A white or almost white crystalline powder

A white crystalline powder

Identification

A:IR

B:TLC

Complies

Solubility

Practically insoluble in water, slightly soluble in ethanol and in methylene chloride.

Complies

Melting point

About 220 °c

222°c

Specific optical rotation

+158°- +167°

+162.0°

Related

Any individual impurity

≤1.0%

0.26%

Total impurities

≤1.5%

0.67%

Not more than one impurity

≥0.5%

Complies

Loss on drying

≤0.5%

0.1%

Assay

97.0%-103.0%

100.1%

 

 

 

 

 

 

 

 

 

Description: A white or almost white,crystalline powder

 

Solubility: Practically insoluble in water,sparingly soluble in ethanol and in methylene chloride

 

Functional use: Mainly used as anti-inflammatory, anti-allergic, anti-toxin, the role of antibodies grams. Biochemical studies, adrenal cortex hormones drugs..

 

 

 

 

 


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